Nurturing brands and technologies for better health worldwide

ABOUT US. Otsuka Nutraceutical Emerging Ventures (“ONCE Ventures”) seeks to deliver a healthier and more sustainable future by empowering visionaries and innovators. As the nutraceuticals venture capital arm of Otsuka Holdings, a global leader in pharmaceutical and nutraceutical products, we invest in entrepreneurs across North America who are at the forefront of innovation and share our passion for delivering better health outcomes. Our approach is simple: Partner with early-stage companies that are working to improve the lives of their consumers and leverage our knowledge and capabilities to propel them forward. Want to work with us? Click here.

Active Nutrition

ACTIVE NUTRITION. A more modern twist on Sports Nutrition. We are interested in nutritional powders, beverages, bars, and emerging forms that deliver the requisite nutrition for an active lifestyle.


Healthy Beverages. Healthy beverages that are not only refreshing, but also have a purpose. We are interested in healthy beverages that provide functional benefits to better the health of consumers.


Plant-Based Foods. Food products for the improvement of consumer and environmental health. We are interested in products ranging from plant-based alternatives to naturally plant-based foods across all eating occasions.


Supplements. Next generation supplements to deliver better health outcomes. We are interested in innovative products, brands, and technologies that deliver superior health outcomes, new form factors, and differentiated brands.

WHO IS OTSUKA. For 100 years, Otsuka has executed its mission of building a healthier world through groundbreaking creativity and innovation. Headquartered in Japan, the company operates multiple brands across Asia, Europe, and North America, with annual revenues of approximately $13 billion. Despite the increase in scale, size, and influence over the years, Otsuka has remained true to its core identity and family roots: A big venture company that thinks unconventionally and challenges the status quo. Read More

With its roots in pharmaceuticals, Otsuka combines its R&D capabilities and deep consumer knowledge to develop a nutraceuticals portfolio that addresses the health needs of everyday consumers. Otsuka’s market-leading brands operate across the growing fields of active nutrition, healthy beverages, plant-based foods, and supplements. Read Less


Daiya®. Leading brand in delicious plant-based and dairy-free foods
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MegaFood®. Fresh From Farm-to-tablet™ pioneer in natural supplements known for their proprietary Slo-Food Process™ manufacturing and transparent supply chain.
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Nature Made®. Leading national vitamin and supplement broadline brand in the United States, trusted by consumers for more than 50 years.
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A legacy of strong partnership. We believe that partnership is the foundation of success. Over the years, we have successfully partnered with leading pharmaceutical and consumer product companies across the world to help products achieve their greatest potential.

Empowering entrepreneurs. Innovation and entrepreneurship is in our DNA. With Otsuka’s own entrepreneurial roots, we seek to empower businesses by offering guidance, expertise, and capabilities for sustainable long-term success.

Track record of building great brands. We have a robust track record of operating and nurturing leading brands in health and wellness, including Nature Made®, Daiya®, and POCARI SWEAT®.

TOOLKIT. We offer a time-tested toolkit dedicated to supporting our portfolio companies wherever they need us to add value.


Robust manufacturing capabilities with proprietary processes and best-in-class quality-control procedures


World class R&D capabilities include product development, clinical research design, and intellectual property protection


Long-tenured relationships with prominent retailers across North America and extensive experience developing cross-channel strategies


Significant regulatory and legal expertise supported by strong manufacturing practices, labeling, and health claims, across domestic and international markets


Proprietary insights, demonstrated brand-building capabilities, and global relationships driven by our portfolio of leading global brands

OUR TEAM. Backed by a world-class operation that has produced truly innovative brands, the ONCE Ventures team has the strategic know-how, global contacts, and brand-building experience needed to help businesses grow

Ara Abrahamian

Ara Abrahamian

Managing Director

Dave Schwendimann

Senior Investment Director

Andrew Goodman

Andrew Goodman

Senior Investment Associate

Bar Lee

Bar Lee

Executive Assistant





May 10, 2023

New Culture’s First Commercial Partner

The company will partner with famous Los Angeles restauranteur Nany Silverton to launch animal-free mozzarella at Pizzeria Mozza in 2024

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November 4, 2021


Proceeds will help the at-home urine diagnostics start-up expand the team and further scale in the US market.

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August 25, 2021


G. Steven Cleere and Les Hine discuss ONCE Ventures and how VC firms actually look at emerging brands

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July 21, 2021

Prenexus Health Closes on Series B Financing

Proceeds enable expansion of state-of-the art facility for producing breakthrough low-dose prebiotic organic PreneXOS

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